Didactic pedagogy is particularly appropriate in specific classroom and learner conditions where structured, direct instruction can maximize learning outcomes. These conditions often involve factors related to the students' prior knowledge, the learning environment, and the nature of the subject matter.

This approach is beneficial when students have low prior knowledge and need a foundational understanding, or when learners benefit from clear, step-by-step guidance, such as those with learning disabilities. In large class sizes, didactic methods allow for efficient delivery of information, while time constraints and high-stakes testing environments necessitate a focus on required content and skills. Safety-critical training demands strict adherence to procedures, making direct instruction essential, and establishing foundational knowledge is crucial for building upon in later learning. Finally, in situations with limited resources, didactic teaching can be a practical option.